About
I built QuestOmics around the questions, not the pipelines.
QuestOmics is a human gut microbiome analysis platform. I focused it on the questions researchers actually ask, not the pipelines that answer them, so you can spend your time on the biology instead of the plumbing.
Sandro Valenzuela
BSc in Bioinformatics · PhD in Infant Gut Microbiome, University of Helsinki
Why I built it
Less plumbing, more biology
Microbiome research moves slowly when most of the work is plumbing. Stitching together tools, formats, and clusters eats the time that should go into asking biological questions. QuestOmics removes that friction: you describe what you want to learn, and the platform runs the right, reproducible analyses for you.
Question-driven analysis
You pick the question
Instead of picking a pipeline and figuring out what it can tell you, you pick a question. “What organisms dominate this community?”, “Are AMR genes present?”, “How does this cohort compare to published studies?” QuestOmics then activates the curated, compatible analyses for it. Incompatible options stay disabled. No manual tool selection. No glue code.
What you can analyze
Built for human gut microbiome data
Supported inputs: shotgun metagenomes (short and long reads), 16S rRNA amplicons, bacterial isolates, and pre-assembled contigs or MAGs.
16S and shotgun metagenomic composition.
Detection of resistance genes across the community.
Which metabolic pathways are active across your samples.
Which species differ between groups, adjusting for covariates.
Your samples next to thousands of published gut metagenomes.
Within and between samples; the standard ecology metrics.
How I keep it honest
Cited interpretation and reproducible runs
Grounded in literature
Tables are not interpretation. Every analysis is paired with Gut Assistant, an AI layer built specifically for microbiome science. It reads from a curated library of peer-reviewed papers and cites only what it can point you to.
Reproducible by design
Every run is sealed and version-pinned, so anyone can reproduce it. Software versions are recorded at execution time, and methods text is auto-generated per run, ready to paste straight into a Materials & Methods section.
Your data stays yours
What happens to your data
Your sequencing data and analysis results belong to you and your study. They are never used for external research, never pooled into external datasets, never sold, and never used to train external models. Data is stored on private, secure hardware in the EU.
Who’s behind it
Built and run by one person


Sandro Valenzuela
BSc in Bioinformatics · PhD in Infant Gut Microbiome, University of Helsinki
QuestOmics is a one-person labor of love right now, built by a microbiome scientist who got tired of the plumbing getting in the way of the questions. If that resonates, I’d love for you to take it for a spin: open a workspace, upload a dataset, and ask your first question. And once you’re inside, reach out through Gut Assistant. I read every message and I’d genuinely like to hear what you’re working on.
Prefer email? I’d love to hear from you, so write to me anytime at svalenzuela@questomics.app.
Let’s talk
Have a question, a dataset, or just feedback?
Tell me what you’re working on, whether it’s a question, a dataset, or something you’re stuck on. I read every message and reply personally.
or copy svalenzuela@questomics.app
